C‐Propargylation Overrides O‐Propargylation in Reactions of Propargyl Chloride with Primary Alcohols: Rhodium‐Catalyzed Transfer Hydrogenation |
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| Authors: | Tao Liang Sang Kook Woo Michael J Krische |
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| Abstract: | The canonical SN2 behavior displayed by alcohols and activated alkyl halides in basic media (O‐alkylation) is superseded by a pathway leading to carbinol C‐alkylation under the conditions of rhodium‐catalyzed transfer hydrogenation. Racemic and asymmetric propargylations are described. |
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| Keywords: | Alkohole Hydrierungen Reaktionsmechanismen Rhodium Synthesemethoden |
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