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Preparation of polyfunctional heterocycles using highly functionalized aminated arylmagnesium reagents as versatile scaffolds
Authors:Lindsay David M  Dohle Wolfgang  Jensen Anne Eeg  Kopp Felix  Knochel Paul
Affiliation:Institut für Organische Chemie, Ludwig-Maximilians-Universit?t München, Butenandtstr. 5-13, Haus F, 81377 München, Germany.
Abstract:[reaction: see text] Functionalized Grignard reagents, derived from readily available o-iodoaniline derivatives and obtained via a straightforward iodine-magnesium exchange, can be used to prepare a wide range of polyfunctional indoles, quinolines, and quinazolinones.
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