|
|||||
|
|
Ultrasound promoted aminolysis of epoxides in aqueous media: a rapid procedure with no pH adjustment for additive-free synthesis of beta-aminoalcohols |
|
| Authors: | Abaee M Saeed Hamidi Vahid Mojtahedi Mohammad M |
| Institution: | aOrganic Chemistry Department, Chemistry and Chemical Engineering Research Center of Iran, P.O. Box 14335-186, Tehran, Iran |
| Abstract: | An efficient and environmentally friendly procedure promoted by ultrasound irradiation is developed for stereoselective ring opening of various epoxides with aromatic and aliphatic amines under aqueous conditions in the presence of no catalyst or additive. Chemoselectivity of the protocol is shown by competition of piperidine and aniline to react with different epoxides resulting in exclusive formation of the respective products of piperidine. |
| Keywords: | Aminolysis Ultrasound irradiation β-Aminoalcohols Aqueous media |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |