Synthesis of substituted pteridines

Conclusions The cyclocondensation of 2,5,6-triamino-4-oxo-3,4-dihydropyrimidine and tetraaminopyrimidine with butylthioacetone and 2-butylthiopropanal gives 7-methylpteridines, while the reaction of these pyrimidine derivatives with 2-phthalimidopropanal, 1,1-dibutoxyacetone, 1,1-dichloroacetone, and 1,1-dibromoacetone gives mixtures of 6- and 7-methylpteridines.Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 2, pp. 452–455, February, 1986.