Summary: Diblock terpolymers that consist of homopolymer and statistical copolymer (polyampholyte) building blocks are synthesized by group transfer polymerization. Two types of block tepolymers are explored in aqueous media: the amphiphilic poly{(diethylamino)ethyl methacrylate]‐co‐(methacrylic acid)}‐block‐poly(methyl methacrylate) and the double hydrophilic polyoligo(ethylene glycol) methacrylate]‐block‐poly{(diethylamino)ethyl methacrylate]‐co‐(methacrylic acid)}. The first terpolymer self‐assembles in aqueous media to form responsive micelles that change their corona charge sign upon switching pH. The second terpolymer exhibits a multi‐responsive behavior. It forms neutral, positive, or negative micelles depending on a combination of different environmental conditions such as temperature, pH, and ionic strength.
