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SYNTHESIS AND CHARACTERIZATION OF HYDROPHOBIC-HYDROPHILIC MULTIBLOCK COPOLYMERS FOR BIOMEDICAL APPLICATIONS*
Authors:Yong Kiel Sung  Yong Joo Kim  Sung Wan Kim
Institution:Department of Chemistry; College of Natural Science; Dongguk University; 3Ga 26; Phildong; Junggu; Seoul 100-715; Korea Reliability Technology Division; NITQ; 2 Chungangdong; Kwachoncity Kyunggido 427-010; Korea Center for Controlled Chemical Delivery; Un
Abstract:The synthesis and characterization of amphiphilic copolymers of poly(dimethyl siloxane)(PDMS),poly(ethylene oxide)(PEO), and heparin(Hep) were investigated. These multiblock copolymers wereidentified using ~1H-NMR, FTIR, end group analysis, and sulfur elemental analysis. The multiblockcopolymers were characterized by using DSC and X-ray diffractometry. The glass transition temperature,crystalline melting characteristics, annealing effect, and cold crystallization of the block copolymers weredetermined by DSC. The crystallinity of the block copolymers was also determined by X-ray diffractionmethod.
Keywords:Heparinized block copolymer  Biomedical polymer  Synthesis  Characterization
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