Interaction of thermal acylacetylenes with thiosemicarbazide and 4-methyl- and 4-phenylthiosemicarbazides

By the reaction of thiosemicarbazide and 4-methyl- and 4-phenylthiosemicarbazides with terminal -acetylenic ketones, depending on the conditions, thiosemicarbazones of acylacetic aldehyde, 1,1-bis(acylvinyl)thiosemicarbazides,and5-phenylamino-2-acylmethyl-3-acylvinyl-1,3,4-thiadiazolinesareobtained. Ring-chain tautomerism of the 1,1-bis(acylvinyl)thiosemicarbazides has been investigated.Irkutsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, 664033 Irkutsk. Translated from Izvestiya Akademii Nauk, Seriya Khimicheskaya, No. 8, pp. 1843–1849, August, 1992.