Structure of macrocyclic alkaloids, oncinotin and isoocinotin |
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| Authors: | M M Badawi A Guggisberg P van den Broek M Hesse H Schmid |
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| Institution: | Organisch-chemisches Institut der Universität Zürich |
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| Abstract: | Two new macrocyclic alkaloids oncinotine ( 1 ) and isooncinotine ( 2 ) have been isolated from Oncinotis nitida BENTH . 1 can be converted into 2 by an amide exchange reaction. The spermidine residue was present in both bases. The structural elucidation was based mainly on (I) the determination of the functional groups, (II) degradation to compounds 12 and 13 and (III) mass spectrometric investigation of 1 and of the above mentioned degradation products. |
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