| A Novel Diterpenoid from the Soft Coral Sarcophyton crassocaule |
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| 作者姓名： | 徐效华 孔垂华 林长江 王昕 朱应栋 杨海申 |
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| 作者单位： | [1]InstituteofElemento-OrganicChemistry,StateKeyLaboratoryofElemento-OrganicChemistry,NankaiUniversity,Tianfin300071,China [2]InstituteofTropicalandSubtropicalEcology,SouthChinaAgriculturalUniversity,Guangzhou,Guangdong510642,China |
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| 基金项目： | ProjectsupportedbytheKeyScienceFoundationofTianjin (No .0 13 80 44 11) |
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| 摘 要： | A novel hydroperoxide cembrane-type diterpenoid was isolated from the soft coral Sarcophyton crassocaule collected from the Xisha Islands in the South China Sea. The structure of 3 was established by spectroscopy and X-ray diffraction analysis,named as sarcophyocrassolide A. It exhibited strong cytotoxicity against the P-388 cell line with IC50 value of 0.1 μg/mL.
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| 关 键 词： | 双萜类化合物 软珊瑚 提取 Sarcophyton-crassocaule 生物活性 抗肿瘤活性 |
A Novel Diterpenoid from the Soft Coral Sarcophyton crassocaule |
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| XU,Xiao-Hua,a KONG,Chui-Hua b LIN,Chang-Jiang a WANG,Xin a ZHU,Ying-Dong a YANG,Hai-Shen a aInstitute of Elemento-Organic Chemistry,State Key Laboratory of Elemento-Organic Chemistry,Nankai University,Tianjin ,China bInstitute of Tropical and Subtropical Ecology,South China Agricultural University,Guangzhou,Guangdong ,China.A Novel Diterpenoid from the Soft Coral Sarcophyton crassocaule[J].Chinese Journal of Chemistry,2003,21(11):1506-1509. |
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| Authors: | XU Xiao-Hua a KONG Chui-Hua b LIN Chang-Jiang a WANG Xin a ZHU Ying-Dong a YANG Hai-Shen a aInstitute of Elemento-Organic Chemistry State Key Laboratory of Elemento-Organic Chemistry Nankai University Tianjin China bInstitute of Tropical and Subtropical Ecology South China Agricultural University Guangzhou Guangdong China |
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| Institution: | XU,Xiao-Hua,a KONG,Chui-Hua b LIN,Chang-Jiang a WANG,Xin a ZHU,Ying-Dong a YANG,Hai-Shen a aInstitute of Elemento-Organic Chemistry,State Key Laboratory of Elemento-Organic Chemistry,Nankai University,Tianjin 300071,China bInstitute of Tropical and Subtropical Ecology,South China Agricultural University,Guangzhou,Guangdong 510642,China |
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| Abstract: | A novel hydroperoxide cembrane‐type diterpenoid was isolated from the soft coral Sarcophyton crassocaule collected from the Xisha Islands in the South China Sea. The structure of 3 was established by spectroscopy and X‐ray diffraction analysis, named as sarcophyocrassolide A. It exhibited strong cytotoxicity against the P‐388 cell line with IC50 value of 0.1 μg/mL. |
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| Keywords: | soft coral Sarcophyton crassocaule sarcophyocrassolide A |
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