| 可双光子激发的聚集诱导发光光敏剂及其生物医学应用 |
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| 引用本文： | 武文博,刘斌.可双光子激发的聚集诱导发光光敏剂及其生物医学应用[J].高等学校化学学报,2020,41(2):191-203. |
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| 作者姓名： | 武文博 刘斌 |
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| 作者单位： | 新加坡国立大学, 化学工程与分子生物工程系, 新加坡 117585 |
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| 基金项目： | Singapore National Research Foundation Competitive Research Program(No.R279-000-483-281);National Research Foundation Investigatorship(No.R279-000-444-281);the National University of Singapore(No.R279-000-482-133)资助 |
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| 摘 要： | 综合评述了双光子激发的聚集诱导发光(AIE)光敏剂的研究进展, 重点讨论了双光子激发的AIE光敏剂的设计思路及在生物医学中的应用, 并对其发展前景进行了展望.
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| 关 键 词： | 聚集诱导发光 光敏剂 光动力治疗 双光子激发 |
| 收稿时间： | 2019-11-26 |
Two-photon Excitable Photosensitizers with Aggregation-induced Emission and Their Biomedical Applications |
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| WU Wenbo,LIU Bin.Two-photon Excitable Photosensitizers with Aggregation-induced Emission and Their Biomedical Applications[J].Chemical Research In Chinese Universities,2020,41(2):191-203. |
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| Authors: | WU Wenbo LIU Bin |
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| Institution: | Department of Chemical and Biomolecular Engineering, National University of Singapore, Singapore 117585, Republic of Singapore |
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| Abstract: | The concept of two-photon excited photodynamic therapy based on photosensitizers with aggregation-induced emission( AIE) takes advantages of high penetration depth and precision from two-photon technology,and high photosensitization efficiency in aggregate state from AIE photosensitizers. In this contribution,we review the recent progress in this field,which includes the design principles of two-photon excitable AIE photosensitizers,specific examples of AIE photosensitizers and their biomedical applications.The perspectives for the future development of this field was also discussed. |
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| Keywords: | Aggregation-induced emission Photosensitizer Photodynamic therapy Two-photon excitation |
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