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Reaction of aminoquinolines with methyl acrylate and transformations of some of the products obtained
Authors:R S Baltrushis  Z -I G Beresnevichyus  A N Machyulis
Institution:(1) Kaunas Polytechnic Institute, USSR
Abstract:3H,4H-Quino1,2-a]-2-pyrimidone, 1-(2-carboxyethyl)aminoquinolinium betaines, and methyl esters of N-quinolinyl-beta-alanines were isolated from the reactions of aminoquinolines with methyl acrylate. Hydrolysis of the latter yielded the corresponding amino acids, two of which were converted to 1-(3- and 6-quinolinyl)dihydrouracils, and the latter was reduced to 1-(6-quinolinyl)-2-oxohexahydropyrimidine.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 482–486, April, 1971.
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