Electroanalysis of dopamine at a gold electrode modified with N-acetylcysteine self-assembled monolayer |
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Authors: | Liu Ting Li Meixian Li Qianyuan |
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Institution: | a Beijing Institute of Pharmacology and Toxicology, Beijing 100850, PR China b College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, PR China |
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Abstract: | Voltammetric behavior of dopamine (DA) on a gold electrode modified with the self-assembled monolayer (SAM) of N-acetylcysteine has been investigated, and one pair of well-defined redox peaks of dopamine is obtained at the SAM modified gold electrode. The oxidation peak current increases linearly with the concentration of dopamine in the range of mol l−1. The detection limit is 8.0×10−7 mol l−1. This method will be applicable to the determination of dopamine in injection of dopamine hydrochloride, and the good recovery of dopamine is obtained. Furthermore, The SAM modified gold electrode can resolve well the voltammetric responses of dopamine and ascorbic acid (AA), so it can also be applied to the determination of dopamine in the presence of ascorbic acid. |
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Keywords: | N-Acetylcysteine Dopamine Ascorbic acid SAM Modified electrode |
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