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3-Trifluoromethyl- and 3-difluoromethyl-thalidomides |
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| Authors: | Sergej N Osipov Lothar Hennig |
| Institution: | a A.N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, Vavilov street 28, GSP-1, RUS 117813 Moscow, Russian Federation b Department of Organic Chemistry, University of Leipzig, Johannisallee 29, D-04103 Leipzig, Germany |
| Abstract: | Syntheses of racemic 3-trifluoromethyl- and 3-difluoromethyl-thalidomide starting from 2-(tert-butyloxycarbonylimino)-3,3,3-trifluoropropionate or -3,3-difluoropropionate as fluorine-containing building blocks are described. |
| Keywords: | 2-Fluoroalkyl-2 5-diaminopent-3-inoates 3-Fluoroalkyl-3-aminopiperidin-2-ones 3-Fluoroalkyl-3-aminopiperidin-2 6-diones |
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