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Isolation, structure elucidation, and total synthesis of two new Chimonanthus alkaloids, chimonamidine and chimonanthidine
Authors:Hiromitsu Takayama  Yohei Matsuda  Kyohei Masubuchi  Atsushi Ishida  Mariko Kitajima  Norio Aimi
Affiliation:Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan
Abstract:Two new tryptamine-related alkaloids, chimonamidine and chimonanthidine, were isolated from the seeds of Chimonanthus praecox Link. and their structures including absolute configuration were elucidated by spectroscopic analysis and biomimetic total synthesis from tryptamine.
Keywords:Alkaloid   Chimonunthus   Isolation   Total synthesis
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