Abstract: | Sesquiterpene lactones of the guaianolide type — isolipidiol (I) and 8-epideacylcynaropicrin (II) — have been isolated from narrow-leaf hawk's-beard,Crepis tectorum L. On the basis of the results of an x-ray experiment the structure of (1R, 3S, 5R, 6R, 7R, 8R)-3,8-dihydroxy-cis,trans-guaia-4(15),10(14),-11(13)-trien-6,12-olide is proposed for (II). |