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Catalytic Ketone Hydrodeoxygenation Mediated by Highly Electrophilic Phosphonium Cations |
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| Authors: | Meera Mehta Dr. Michael H. Holthausen Ian Mallov Dr. Manuel Pérez Dr. Zheng‐Wang Qu Prof. Dr. Stefan Grimme Prof. Dr. Douglas W. Stephan |
| Affiliation: | 1. Department of Chemistry, University of Toronto, 80 St. George St, Toronto Ontario M5S 3H6 (Canada);2. Mulliken Center for Theoretical Chemistry, Institut für Physikalische und Theoretische Chemie, Universit?t Bonn, Beringstrasse 4, 53115 Bonn (Germany) |
| Abstract: | Ketones are efficiently deoxygenated in the presence of silane using highly electrophilic phosphonium cation (EPC) salts as catalysts, thus affording the corresponding alkane and siloxane. The influence of distinct substitution patterns on the catalytic effectiveness of several EPCs was evaluated. The deoxygenation mechanism was probed by DFT methods. |
| Keywords: | density functional calculations hydrosilylation Lewis acids phosphorus synthetic methods |