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A Synthetic DNA‐Binding Domain Guides Distinct Chromatin‐Modifying Small Molecules to Activate an Identical Gene Network
Authors:Le Han  Dr Ganesh N Pandian  Anandhakumar Chandran  Shinsuke Sato  Junichi Taniguchi  Dr Gengo Kashiwazaki  Yoshito Sawatani  Kaori Hashiya  Dr Toshikazu Bando  Prof Yufang Xu  Prof Xuhong Qian  Prof Hiroshi Sugiyama
Institution:1. Department of Chemistry, Graduate School of Science, Kyoto University Kitashirakawa‐Oiwakecho, Sakyo‐ku, Kyoto 606‐8502 (Japan);2. Shanghai Key Laboratory of Chemical Biology, State Key Laboratory of Bioreactor Engineering, School of Pharmacy, East China University of Science and Technology, Meilong Road 130, Shanghai, 200237 (China);3. Institute for Integrated Cell‐Material Sciences (WPI‐iCeMS), Kyoto University Yoshida‐Ushinomiyacho, Sakyo‐ku, Kyoto 606‐8501 (Japan)
Abstract:
Keywords:DNA recognition  epigenetics  gene expression  histone modification  synthetic biology
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