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Inside Cover: Stereoselective Synthesis of the Halaven C14–C26 Fragment from D‐Quinic Acid: Crystallization‐Induced Diastereoselective Transformation of an α‐Methyl Nitrile (Angew. Chem. Int. Ed. 17/2015)
Authors:Francis Belanger  Dr. Charles E. Chase  Dr. Atsushi Endo  Dr. Francis G. Fang  Dr. Jing Li  Steven R. Mathieu  Dr. Annie Z. Wilcoxen  Huiming Zhang
Affiliation:1. Current address: PCAS BioMatrix, 725 Trotter St., Saint‐Jean‐sur‐Richelieu, Quebec J3B 8?J8 (Canada);2. Next Generation Systems, Eisai Inc. 4 Corporate Drive, Andover, MA 01810 (USA);3. Current address: Amgen, One Kendall Square, 360 Binney St. Cambridge, MA 02142 (USA);4. Current address: Johnson Matthey Pharma Services, 75 Patton Rd. Devens, MA 01434 (USA)
Abstract:
Keywords:antitumor agents  asymmetric synthesis  chiral pool  green chemistry  total synthesis
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