Selective Michael Reaction Controlled by Supersilyl Protecting Group |
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| Authors: | Dr. Atsuto Izumiseki Prof. Dr. Hisashi Yamamoto |
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| Affiliation: | Molecular Catalyst Research Center, Chubu University, 1200 Matsumoto‐cho, Kasugai, Aichi 487‐8501 (Japan) |
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| Abstract: | Selective Michael reaction of organolithium reagents to supersilyl methacrylate is reported. The method was able to control a single and double Michael addition. The successful termination of the process using the supersilyl protecting group allows for the controlled, chemoselective, and diastereoselective Michael reaction. |
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| Keywords: | chemoselectivity Michael reaction protecting groups supersilyl group synthetic methods |
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