Catalytic Intramolecular Aminofluorination,Oxyfluorination, and Carbofluorination with a Stable and Versatile Hypervalent Fluoroiodine Reagent |
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| Authors: | Dr. Weiming Yuan Prof. Kálmán J. Szabó |
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| Affiliation: | Department of Organic Chemistry, Stockholm University (Sweden) http://www.organ.su.se/ks/ |
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| Abstract: | Application of a fluoroiodine analogue of the Togni reagent was studied in fluorocyclization reactions. In the presence of a transition‐metal catalyst the applied fluoroiodine reagent can be used for aminofluorination, oxyfluorination, and carbofluorination reactions. The described procedure has a very broad synthetic scope for preparation of functionalized hetero‐ and isocyclic compounds having a tertiary fluorine substituent. |
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| Keywords: | copper cyclizations fluorine heterocycles homogeneous catalysis |
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