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Well‐Defined and Robust Rhodium Catalysts for the Hydroacylation of Terminal and Internal Alkenes |
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| Authors: | Dr Amparo Prades Dr Maitane Fernández Dr Sebastian D Pike Prof Michael C Willis Prof Andrew S Weller |
| Institution: | Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA (UK) |
| Abstract: | A Rh‐catalyst system based on the asymmetric ligand tBu2PCH2P(o‐C6H4OMe)2 is reported that allows for the hydroacylation of challenging internal alkenes with β‐substituted aldehydes. Mechanistic studies point to the stabilizing role of both excess alkene and the OMe‐group. |
| Keywords: | catalysis hydroacylation phosphine rhodium |