| 超高效液相色谱串联质谱法测定化妆品中10种性激素残留 |
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| 引用本文： | 贾丽,刘希诺,王荣艳,王颖,刘艳. 超高效液相色谱串联质谱法测定化妆品中10种性激素残留[J]. 分析试验室, 2011, 30(6): 57-60 |
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| 作者姓名： | 贾丽 刘希诺 王荣艳 王颖 刘艳 |
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| 作者单位： | 北京市理化分析测试中心北京100089 |
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| 基金项目： | 北京市科学技术研究院创新工程项目 |
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| 摘 要： | 采用超高效液相色谱-串联电喷雾四极杆质谱在多反应监测模式下测定了特殊功效类化妆品中10种性激素的残留.样品按照不同剂型分别前处理,目标物以乙腈/水为流动相,经C18色谱柱分离.在超高效液相色谱串联质谱分析过程中以保留时间和离子对(母离子和两个碎片离子)信息比较定性,以母离子和响应值高的碎片离子进行定量.方法检出限为0....
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| 关 键 词： | 超高效液相色谱串联质谱 性激素 化妆品 |
Determination of ten sex hormones in cosmetic by ultra performance liquid chromatography mass spectrometry |
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| JIA Li,LIU Xi-nuo,WANG Rong-yan,WANG Ying,LIU Yan. Determination of ten sex hormones in cosmetic by ultra performance liquid chromatography mass spectrometry[J]. Chinese Journal of Analysis Laboratory, 2011, 30(6): 57-60 |
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| Authors: | JIA Li LIU Xi-nuo WANG Rong-yan WANG Ying LIU Yan |
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| Affiliation: | JIA Li,LIU Xi-nuo,WANG Rong-yan,WANG Ying and LIU Yan(Beijing center for physical and chemical analysis,Beijing 100089) |
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| Abstract: | Ten sex hormones in cosmetic were determined by ultra performance liquid chromatography mass spectrometry in multi-reaction monitoring mode.Various cosmetic samples were extracted with different solvents.Ten sex hormones were separated on a C18 column with acetonitrile/water as the mobile phase.Retention times and charge-mass ratio of compounds(parent ion and two fragment ions) were used for qualitative analysis,and the peak areas of parent ion and fragment ions on high intensity were used for quantitative ... |
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| Keywords: | Ultra performance liquid chromatography mass spectrometry Sex hormones Cosmetic |
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