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Toward the synthesis of spirastrellolide B: a synthesis of the C1-C23 subunit
Authors:Keaton Katie A  Phillips Andrew J
Affiliation:Department of Chemistry and Biochemistry, University of Colorado at Boulder, Boulder, CO 80309-0215, USA.
Abstract:A synthesis of the C1-C23 subunit of spirastrellolide B is described. The synthesis features two applications of a Kulinkovich-cyclopropanol ring-opening strategy for the coupling of esters with olefins to produce ketones.
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