Identical photosensitizing activities of a sulfonated aluminium phthalocyanine on human erythroleukemia cell lines susceptible or resistant to the cytotoxic activity of doxorubicin. |
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| Authors: | C Tempête C Giannotti G H Werner |
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| Affiliation: | Institut de Chimie des Substances Naturelles, Centre National de la Recherche Scientifique, Gif sur Yvette, France. |
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| Abstract: | In this paper we report that a human erythroleukemia cell line made 100 times more resistant than the parental line to the cytostatic activity of doxorubicin and spontaneously 500-1000 times more resistant to the cytostatic activity of an unrelated drug, namely taxol, exhibits on the other hand unchanged susceptibility to the photosensitizing activity of a sulfonated phthalocyanine. |
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