| SDS胶束体系中亚甲蓝与血清白蛋白的相互作用 |
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| 引用本文： | 郭荣,范国康,刘天晴,焦新安. SDS胶束体系中亚甲蓝与血清白蛋白的相互作用[J]. 物理化学学报, 2001, 17(2): 185-188. DOI: 10.3866/PKU.WHXB20010220 |
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| 作者姓名： | 郭荣 范国康 刘天晴 焦新安 |
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| 作者单位： | Department of Chemistry and Chemical Engineering, Science School,Yangzhou University;Yang Zhou 225002；Biological Science and Technology School, Yangzhou University, Yangzhou 225009 |
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| 基金项目： | 国家自然科学基金(29733110,20073038)资助项目 |
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| 摘 要： | The interaction of methylene blue(MB) and bovine serum albumin(BSA) is investigated in the SDS micelle system which is simulated as one kind of coexisted albumin. The interaction parameters of MB and BSA and simulated albumin such as partition coefficient 辍ormal binding free energy 腉、average binding number n are calculated. The results show that most of MB is in the form of monomer in SDS micelle systems；the main interaction of MB and BSA is of static electric and H bind force,and that of MB and simulated albumin is only of static electric force.
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| 关 键 词： | 亚甲蓝(MB) 牛血清白蛋白(BSA) 模拟蛋白 SDS胶束 |
| 收稿时间： | 2000-06-10 |
| 修稿时间： | 2000-06-10 |
The Interaction of Methylene Blue and Bovine Serum Albumin in SDS Micelle System |
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| Guo Rong,FAN Guo-Kang,LIU Tian-qing,JIAO Xin-an. The Interaction of Methylene Blue and Bovine Serum Albumin in SDS Micelle System[J]. Acta Physico-Chimica Sinica, 2001, 17(2): 185-188. DOI: 10.3866/PKU.WHXB20010220 |
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| Authors: | Guo Rong FAN Guo-Kang LIU Tian-qing JIAO Xin-an |
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| Affiliation: | Department of Chemistry and Chemical Engineering, Science School,Yangzhou University;Yang Zhou 225002；Biological Science and Technology School, Yangzhou University, Yangzhou 225009 |
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| Abstract: | The interaction of methylene blue(MB) and bovine serum albumin(BSA) is investigated in the SDS micelle system which is simulated as one kind of coexisted albumin. The interaction parameters of MB and BSA and simulated albumin such as partition coefficient κ 、 normal binding free energy Δ G 、 average binding number n are calculated. The results show that most of MB is in the form of monomer in SDS micelle systems； the main interaction of MB and BSA is of static electric and H-bind force,and that of MB and simulated albumin is only of static electric force. |
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| Keywords: | Methylene blue Bovine serum albumin Simulated albumin SDS micelle |
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