| Abstract: | The polymerization of the previously reported allyl and diallyl quaternary ammonium salts, which from vesicles in water, to their polymerized analogs was further investigated. The structure of the polymer derived from the diallyl derivative, for which some controversy existed, was elucidated by 13C-NMR spectroscopy. Mixed vesicles, based on the monoallyl monomer and incorporating certain vesicle forming quaternary ammonium salts, cholesterol, or cholesteryl acrylate were also formed. These mixed vesicles were characterized primarily as far as their stability is concerned. It was found that the incorporation of the additives does not enhance the stability of the mixed vesicles compared to that exhibited by monoallyl simple vesicles. In addition, polymerization of mixed monoallyl-cholesteryl acrylate vesicles results in the destruction of their structure. On the contrary, simple polymerized vesicles, resulting from the diallyl monomer, showed excellent long-term stability. Specifically, samples prepared two years ago are still dispersed and, very possibly, they will remain so for a longer period since they are not showing signs of precipitation. |
