1,3-Dipolar cycloadditions of azomethine ylides with dipolarophiles. II. Synthesis of pyrrolizidines |
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| Authors: | F. Orsini F. Pelizzoni M. Forte M. Sisti F. Merati P. Gariboldi |
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| Abstract: | Substituted pyrrolizidines have been synthesized by 1,3-dipolar cycloaddition of various dipolarophiles with the azomethine ylide generated by treatment of proline with benzaldehyde in dimethylsulfoxide. The regio- and stereochemical outcome of the reaction as well as the stability of the isomers obtained are discussed. |
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