Measurement of specific absorption rate for clinical EPR at 1200 MHz |
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Authors: | I Kh Salikhov H M Swartz |
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Institution: | (1) Research and Development Center for Microtherapy, EFMT, D-44799 Bochum, Germany;(2) TFH University of Applied Sciences, D-13353 Berlin, Germany;(3) Charit, Medizinische Fakultt, Institut fr Radiologie, Humboldt-Universitt zu Berlin, D-10117 Berlin, Germany;(4) Grnemeyer Institute for Microtherapy, University of Witten/Herdecke, D-44799 Bochum, Germany |
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Abstract: | The specific absorption rate (SAR) has been measured experimentally at 1200 MHz under the conditions and in the configuration
used for in vivo electron paramagnetic resonance (EPR) spectroscopy of human subjects. The measurement of SAR was based on
an analysis of the time dependence of the temperature of a model tissue (isolated bovine skeletal muscle) placed adjacent
to the surface loop of the EPR resonator. The measured SAR in the tissue at the position that should have the greatest density
of microwaves, directly under the wire of the loop, was 3.7±1.2 W/kg at 100 mW incident radio-frequency power to a surface
loop resonator with an efficiency of about 0.1 mT/W1/2. This is substantially below the recommended limit in the relevant regulation for extremities. The method of measurement
of SAR used in this study can be adapted for other resonators and other types of clinical applications of EPR spectroscopy
and imaging. |
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