| A new triterpene glycoside from sea cucumber Holothuria leucospilota |
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| 引用本文： | Hua Han,Yang Hua Yi,Ling Li,Xiao Hua Wang,Bao Shu Liu,Peng Sun,Min Xiang Pan Research Center for Marine Drugs,School of Pharmacy,Second Military Medical University,Shanghai 200433,China. A new triterpene glycoside from sea cucumber Holothuria leucospilota[J]. 中国化学快报, 2007, 18(2): 161-164. DOI: 10.1016/j.cclet.2006.12.027 |
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| 作者姓名： | Hua Han Yang Hua Yi Ling Li Xiao Hua Wang Bao Shu Liu Peng Sun Min Xiang Pan Research Center for Marine Drugs School of Pharmacy Second Military Medical University Shanghai 200433 China |
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| 作者单位： | Hua Han，Yang Hua Yi，Ling Li，Xiao Hua Wang，Bao Shu Liu，Peng Sun，Min Xiang Pan Research Center for Marine Drugs，School of Pharmacy，Second Military Medical University，Shanghai 200433，China |
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| 基金项目： | 国家高技术研究发展计划(863计划) |
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| 摘 要： | A new triterpene glycoside, leucospilotaside A, along with a known saponin, isolated from sea cucumber Holothuria leucospilota, and its structure was elucidated as 3β-O-[4-O-sodiumsulfate-β-D-quinovopyranosyl-(1→2)-β-D-xylopyranosyl]-holosta-22-ketone-9-en-17α,25α-diol (1) by extensive spectroscopic analysis and chemical methods. Leucospilotaside A (1) has a ketone carbonyl group (22) in the aglycon side chain.
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| 收稿时间： | 2006-08-30 |
A new triterpene glycoside from sea cucumber Holothuria leucospilota |
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| Hua Han,Yang Hua Yi,Ling Li,Xiao Hua Wang,Bao Shu Liu,Peng Sun,Min Xiang pan. A new triterpene glycoside from sea cucumber Holothuria leucospilota[J]. Chinese Chemical Letters, 2007, 18(2): 161-164. DOI: 10.1016/j.cclet.2006.12.027 |
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| Authors: | Hua Han Yang Hua Yi Ling Li Xiao Hua Wang Bao Shu Liu Peng Sun Min Xiang pan |
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| Affiliation: | Research Center for Marine Drugs, School of Pharmacy, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | A new triterpene glycoside, leucospilotaside A, along with a known saponin, isolated from sea cucumber Holothuria leucospilota, and its structure was elucidated as 3β-O-[4-O-sodiumsulfate-β-d-quinovopyranosyl-(1 → 2)-β-d-xylopyranosyl]-holosta-22-ketone-9-en-17α,25α-diol (1) by extensive spectroscopic analysis and chemical methods. Leucospilotaside A (1) has a ketone carbonyl group (22) in the aglycon side chain. |
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| Keywords: | Sea cucumber Holothuria leucospilota Triterpene glycoside Leucospilotaside A |
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