| Study on the stannous halides promoted addition of 1,1,1-trichloro-2,2,2-trifluoroethane to aldehydes and the chemical transformation thereof |
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| 作者姓名： | HU Chang-Ming CHEN JianShanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai China |
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| 作者单位： | HU，Chang-Ming CHEN，JianShanghai Institute of Organic Chemistry，Chinese Academy of Sciences，Shanghai 200032，China |
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| 基金项目： | Project supported by the National Natural Science Foundation of China. |
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| 摘 要： | Promoted by stannous salts, 1,1,1-trichloro-2,2,2-trifluoroethane reacts readily with aliphatic, aromatic, and α, β-unsaturated aldehydes giving the corresponding alcohols bearing a CF3CCl2-moiety in good to excellent yields. These alcohols are farther oxidized by Jones reagent giving the corresponding ketones in high yields.
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Study on the stannous halides promoted addition of 1,1,1-trichloro-2,2,2-trifluoroethane to aldehydes and the chemical transformation thereof |
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| HU,Chang-Ming CHEN,JianShanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai ,China.Study on the stannous halides promoted addition of 1,1,1-trichloro-2,2,2-trifluoroethane to aldehydes and the chemical transformation thereof[J].Chinese Journal of Chemistry,1994,12(2):183-189. |
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| Authors: | HU Chang-Ming CHEN Jian |
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| Institution: | HU,Chang-Ming CHEN,JianShanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,China |
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| Abstract: | Promoted by stannous salts, 1,1,1-trichloro-2,2,2-trifluoroethane reacts readily with aliphatic, aromatic, and α,β-unsaturated aldehydes giving the corresponding alcohols bearing a CF3CCl2-moiety in good to excellent yields. These alcohols are further oxidized by Jones reagent giving the corresponding ketones in high yields. |
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| Keywords: | 1 1 1-Trichloro-2 2 2-trifluoroethane aldehydes stannous halides addition Jones oxidation ketones |
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