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Synthesis of new, BODIPY-based sensors and labels
Authors:Tamás Kálai
Institution:Institute of Organic and Medicinal Chemistry, University of Pécs, PO Box 99, H-7602 Pécs, Hungary
Abstract:New, 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) dye based thiol-reactive fluorescent label, fluorescent amino acid, and fluoroionophore compounds with 540-560 nm emission are described. Combination of a BODIPY dye with a nitronyl nitroxide or an imino nitroxide or a bifunctional pyrroline nitroxide furnished a nitric oxide, a redox sensitive molecule and a double (spin and fluorescence) label, respectively.
Keywords:Fluorescence  Crown ethers  Amino acid  Nitroxides  Double sensors
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