A new one-pot synthesis of Gb3 and isoGb3 trisaccharide analogues |
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Authors: | Changning Wang |
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Affiliation: | The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd #38, Beijing 100083, China |
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Abstract: | Gb3 and isoGb3 are both biologically important oligosaccharides. A new efficient synthesis of Gb3 and isoGb3 trisaccharide analogues has been achieved by one-pot sequential glycosylation strategy starting from simple monosaccharide building blocks promoted by N-(phenylthio)-?-caprolactam at room temperature. |
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Keywords: | Gb3 isoGb3 Thioglycoside One-pot synthesis Glycosylation |
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