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A new one-pot synthesis of Gb3 and isoGb3 trisaccharide analogues
Authors:Changning Wang
Affiliation:The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Xue Yuan Rd #38, Beijing 100083, China
Abstract:Gb3 and isoGb3 are both biologically important oligosaccharides. A new efficient synthesis of Gb3 and isoGb3 trisaccharide analogues has been achieved by one-pot sequential glycosylation strategy starting from simple monosaccharide building blocks promoted by N-(phenylthio)-?-caprolactam at room temperature.
Keywords:Gb3   isoGb3   Thioglycoside   One-pot synthesis   Glycosylation
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