A novel conversion of acetylenic 1,2,4-triazoles into 3-alkyl-5-arylpyridazines |
| |
| Authors: | Patrick J Crowley Sally E Russell Laurence G Reynolds |
| |
| Institution: | Syngenta, Jealott's Hill International Research Centre, Bracknell, Berkshire RG42 6EY, UK |
| |
| Abstract: | Bromination of 2-aryl-1-1,2,4]triazol-1-ylalk-3-yn-2-ols gives 6-bromo-7-hydroxy-5-alkyl-7-aryl-7,8-dihydro-1,2,4]triazolo1,2-a]pyridazin-4-ylium salts, which are converted by treatment with strong alkali into novel 3-alkyl-5-arylpyridazines. |
| |
| Keywords: | Pyridazines Triazoles Acetylenes Triazolium Cyclisation |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
