A multicomponent approach to substituted benzenes involving sequential nickel-catalyzed reactions |
| |
| Authors: | Ahmad Samih ElDouhaibi Mario Lozanov |
| |
| Institution: | a Department of Chemistry, University of Michigan, 930 N. University Ave. Ann Arbor, MI 48109-1055, USA
b Department of Chemistry, Wayne State University, Detroit, MI 48202-3489, USA |
| |
| Abstract: | Two sequential nickel-catalyzed reactions allow the preparation of highly functionalized alkylidene cyclohexenols. Dehydration of the resulting cycloadducts allows the preparation of densely functionalized aromatic ring systems, whereas a simple sequence involving oxidation followed by carbonyl addition or enolization allows additional diversity incorporation. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
