Preparation of optically pure fused polycyclic scaffolds by Ugi reaction followed by olefin and enyne metathesis |
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| Authors: | Andrea Basso |
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| Institution: | Università degli Studi di Genova, Dipartimento di Chimica e Chimica Industriale, Via Dodecaneso 31, 16146 Genova, Italy |
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| Abstract: | Optically pure fused polycyclic scaffolds containing up to eight stereocentres have been synthesised by olefin metathesis and tandem enyne metathesis/Diels-Alder addition of Ugi multicomponent reaction adducts generated from 7-oxa-2.2.1]-bicyclic amino acid derivatives. |
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