Synthesis and Hemolytic Properties of Glycyrrhetic Acid Glycosides |
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Authors: | Nisar Ullah Werner Seebacher Robert Weis Johann Jurenitsch Katharina Rauchensteiner Ernst Haslinger |
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Affiliation: | (1) Institute of Pharmaceutical Chemistry, University of Graz, Graz, Austria, AT;(2) Institute of Pharmacognosy, University of Vienna, Vienna, Austria, AT |
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Abstract: | Summary. The synthesis of monodesmosidic glycyrrhetic acid disaccharides via its diphenylmethyl ester is described. Their hemolytic activity is lower as compared to the corresponding oleanolic aciddisaccharides. The influence of the structure of the aglycon on the hemolytic activity is discussed. Received November 18, 1999. Accepted November 30, 1999 |
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Keywords: | . Hemolytic activity Glycosidation Glycyrrhetic acid Disaccharides. |
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