Synthesis of some new types of 3-coumarinyl-substituted pyrazolopyrimidines and imidazothiazoles

The treatment of 3-3-(dimethylamino)-1-oxo-2-propenyl]chromen-2-ones with 3-amino-4-cyanopyrazole gives 7-(2-oxo-2H-chromen-3-yl)pyrazolo1,5-a]pyrimidine-3-carbonitriles. The reaction of 3-(2-bromoacetyl)coumarins with 2-amino-4-(methoxycarbonylmethyl)thiazole and 2-amino-4-methylthiazole gives methyl 2-(6-(2-oxo-2H-chromen-3-yl)imidazo2,1-b]thiazol-3-yl)acetate and 3-(2-methylimidazo2,1-b]thiazol-6-yl)-2H-chromen-2-ones, respectively. __________ Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 465–471, March, 2008.