Efficient multigram synthesis of the repeating unit of gallic acid-triethylene glycol dendrimers |
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| Authors: | Amaral Sandra P Fernandez-Villamarin Marcos Correa Juan Riguera Ricardo Fernandez-Megia Eduardo |
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| Affiliation: | Department of Organic Chemistry and Center for Research in Biological Chemistry and Molecular Materials (CIQUS), University of Santiago de Compostela, Jenaro de la Fuente s/n, 15782 Santiago de Compostela, Spain. |
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| Abstract: | A multigram synthesis of the repeating unit of GATG (gallic acid-triethylene glycol) dendrimers is described through an efficient and cost-effective route. These conditions overcome major problems precluding scaling up and afford product in excellent overall yield and purity. Special attention has been paid in this process to green chemistry principles: atom economy, safety, and waste reduction. This scheme could be easily adapted for the preparation of similar dendritic systems. |
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