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Enantioselective formal synthesis of antitumor agent (+)-ottelione A
Authors:Mi Young Lee  Shuai Jiang  Jae Yi Sim  Do Hyun Ryu
Institution:a Department of Chemistry, Sungkyunkwan University, Suwon 440-746, Republic of Korea
b Korea Basic Science Institute, 5St, Anam-Dong, Seongbuk-Gu, Seoul 136-701, Republic of Korea
Abstract:The enantioselective formal synthesis of a natural antitumor product, (+)-ottelione A, was achieved through a catalytic enantioselective Diels-Alder strategy. These endeavors have led to the synthesis of a variety of synthetic analogues of this biologically potent natural product.
Keywords:
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