亚临床肝性脑病患者的血清锌,铜含量的测定及临床意义

检测了３０例慢性活动性肝炎患者、３０例肝硬化患者、３０例亚临床肝性脑病患者血清中的铜、锌含量，并与正常对照组进行比较分析，探讨了微量元素铜、锌的血清含量改变及其影响因素，分析其临床意义。结果表明体内的铜锌含量与肝脏功能有密切的关系。在慢性活动性肝炎时，虽然肝脏功能有一定的损害，但由于肝脏的代偿能力强，铜，锌含量仍可保持在正常水平，而在肝硬化、亚临床肝性脑病时，铜锌明显降低，而铜锌含量的降低又导致机

Quantitative Analysis and Clinical Significance of Serum Zinc and Copper in Subclinical Hepatic Encephalopathy

The trace elements zinc and copper in serum were tested in 30 patients of chronic active hepatitis, 30 patients of hepatic cirrhosis. 30 patients of subclinical hepatic encephalopathy and a control group, in order to investigate the change of their concentration in blood and affecting factors. As a result. the contents of zinc and copper in body are closely related to hepatic function. In chronic active hepatitis. although the hepatic function has been damaged, the contents of zinc and copper have remained the normal level because of the enough compensation. However. in the patients with hepatic cirrhosis and subclinical hepatic encephalopathy the contents of zinc and copper are greatly reduced. which resulted in the decrease of the activity of many enzymes. and the more degeneration of the body function. Therefore. the quantitative analysis of the serum zinc and copper is helpful to the judgement and treatment of hepatic diseases.