Novel two-step, one-pot synthesis of primary acylureas |
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Authors: | Zili Xiao Andrew J. Tebben Michael A. Galella David S. Weinstein |
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Affiliation: | Research & Development, Britstol-Myers Squibb Company, Route 206 & Provinceline Road, Princeton, NJ 08543, USA |
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Abstract: | A new procedure for the synthesis of primary acylureas from cyanamide and a variety of carboxylic acids is described. Under mild reaction conditions, the products were obtained in good yield from commercially available starting materials. |
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