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A novel symmetric sulfur-containing biscembranoid from the Formosan soft coral Sinularia flexibilis |
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| Authors: | Bo-Wei Chen Jui-Hsin Su Chang-Feng Dai Jyh-Horng Sheu |
| Affiliation: | a Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan b Taiwan Coral Research Center, National Museum of Marine Biology & Aquarium, Checheng, Pingtung 944, Taiwan c Institute of Oceanography, National Taiwan University, Taipei 112, Taiwan d Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan |
| Abstract: | A structurally unique symmetric sulfur-containing biscembranoid, namely, thioflexibilolide A (1), was isolated from the soft coral Sinularia flexibilis. The structure was determined by extensive spectroscopic analyses. Compound 1 has been found to possess significant anti-inflammatory and neuroprotective activities. |
| Keywords: | Soft coral Sinularia flexibilis Thioflexibilolide A Anti-inflammatory activity Neuroprotective activity |
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