One-pot synthesis of 2-aminobenzimidazoles using 2-chloro-1,3-dimethylimidazolinium chloride (DMC) |
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| Authors: | Gerald D. Artman III |
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| Affiliation: | Global Discovery Chemistry, Novartis Institutes for BioMedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA |
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| Abstract: | 2-Chloro-1,3-dimethylimidazolinium chloride (DMC or DMC-Cl) has been found to effectively and rapidly generate 2-aminobenzimidazoles from 1,2-diaminoarenes and isothiocyanates in moderate to good yields at room temperature in a one-pot operation. |
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