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Simple pyridylmethylamines: efficient and robust N,N-ligands for Suzuki-Miyaura coupling reactions
Authors:Maria-Agatha Gunawan  Chunjing Qiao  Isabelle Abrunhosa-Thomas  Bertrand Puget  Jean-Philippe Roblin  Damien Prim  Yves Troin
Institution:a Clermont Université, ENSCCF, EA 987, LCHG, BP 10448, F-63000 Clermont-Ferrand, France
b Ensemble scientifique des Cézeaux, 24, Avenue des Landais, BP10187, 63174 Aubière Cedex, France
c Université de Versailles-Saint-Quentin, Institut Lavoisier de Versailles (ILV), UMR CNRS 8180, 45 avenue des Etats-Unis, 78035 Versailles Cedex, France
Abstract:A series of pyridylmethylamines have been synthesized in one step from commercially available starting material and identified as effective ligands for Pd-catalyzed carbon-carbon bond formation through Suzuki-Miyaura coupling reaction. The N,N-pyridylmethylamine-Pd catalytic systems appeared as an interesting and robust compromise between catalytic efficiency, substrate compatibility, and practical aspects.
Keywords:Pyridylmethylamines  N  N-Ligands  Suzuki-Miyaura
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