Straightforward synthesis of 3′-deoxy-3′,4′-didehydronucleoside-5′-aldehydes via 2′,3′-O-orthoester group elimination: a simple route to 3′,4′-didehydronucleosides |
| |
| Authors: | Magdalena Petrová |
| |
| Institution: | Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, v. v. i., Flemingovo nám. 2, 166 10 Prague 6, Czech Republic |
| |
| Abstract: | Straightforward, high-yielding syntheses of 3′-deoxy-3′,4′-didehydronucleoside-5′-aldehydes and 3′-deoxy-3′,4′-didehydronucleosides starting from 2′,3′-O-orthoester derivatives of ribonucleosides are described. |
| |
| Keywords: | Moffat oxidation β-Elimination Nucleoside-5&prime -aldehydes 3&prime 4&prime -Didehydronucleosides 2&prime 3&prime -O-Orthoester |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
