Dehydrative intramolecular nitrone cycloaddition in confined aqueous media: a green chemical route to cis-fused chromano[4,3-c]isoxazoles |
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| Authors: | Amrita Chatterjee Sandip K. Hota Pranab K. Bhattacharya |
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| Affiliation: | a Chemistry Division, Indian Institute of Chemical Biology, Kolkata 700 032, India
b Chemistry Group, Birla Institute of Science and Technology, Pilani - K. K. Birla, Goa Campus, Goa 403 726, India |
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| Abstract: | An efficient synthetic route to the formation of cis-fused chromano[4,3-c]isoxazoles via dehydrative intramolecular 1,3-dipolar nitrone cycloaddition in organized aqueous media in the presence of a surfactant (viz. CTAB) as catalyst was developed, which indeed appeared to be green and a more sustainable method than the existing methods with the additional advantage of easy isolation of products. |
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| Keywords: | Nanoreactor Dehydration reaction in water Intramolecular nitrone cycloaddition Chromano[4,3-c]isoxazoles |
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