Aminocalix[4]arene: the effect of pH on the dynamics of gate and portals on the hydrophobic cavity |
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| Authors: | Satish Balasaheb Nimse Junghoon Kim Van-Thuan Nguyen Chan-Yong Jung Taisun Kim |
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| Institution: | a Institute for Applied Chemistry and Department of Chemistry, Hallym University, Chuncheon 200-702, Republic of Korea
b Biometrix Technology, Inc., 202 BioVenture Plaza, Chuncheon 200-161, Republic of Korea |
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| Abstract: | The pH of a solution shows a significant effect on the dynamics of the gate (formed by eight benzylic functions) and portal on the hydrophobic cavity of receptor. At pH 5.8 the gate closes and prohibits the entry of anionic guests. However, at pH 7.3 the gate opens and allows the entry of anionic guests into the hydrophobic cavity. It is the first time that anionic receptor efficiently recognizes anionic guests. |
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| Keywords: | Calix[4]arene Molecular recognition Receptor Host-guest systems Gate and portals Hydrophobic cavity |
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