Efficient S-alkylation of cysteine in the presence of 1,1,3,3-tetramethylguanidine |
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Authors: | Marek W?ostowski Sylwia Czarnocka Piotr Maciejewski |
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Institution: | Laboratory of Technological Processes, Faculty of Chemistry, Warsaw University of Technology, ul. Noakowskiego 3, 00-664 Warsaw, Poland |
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Abstract: | The synthesis of S-alkylated cysteine derivatives was carried out successfully in the presence of 1,1,3,3-tetramethylguanidine. Alkylation proceeded in high yields on unprotected amino acids and peptides containing a sulfhydryl group. |
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