|
|||||
|
|
On the preparation of azepinones |
|
| Authors: | Galyna G Dubinina William J Chain |
| Institution: | a Department of Chemistry, 2545 McCarthy Mall, University of Hawaii, Honolulu, HI 96822, United States b The Cancer Research Center of Hawaii, 651 Ilalo Street, Honolulu, HI 96813, United States |
| Abstract: | We report here a simple and efficient preparation of 1H-azepin-5(2H)-ones and their unexpectedly facile isomerization to 1H-azepin-5(4H)-ones under mildly basic reaction conditions. |
| Keywords: | Azepinone Diels-Alder Cycloaddition Isomerization Ring-expansion Synthesis |
| 本文献已被 ScienceDirect 等数据库收录！ | |