A simple, solvent and catalyst-free green synthesis of novel N-[(1H-indol-3-yl)arylmethyl]heteroarylamines |
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| Authors: | Abolfazl Olyaei Bahareh Shams Fatemeh Gesmati |
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| Institution: | a Department of Chemistry, Payame Noor University (PNU), Qazvin, Iran
b Department of Chemistry, Islamic Azad University, Takestan Branch, Qazvin, Iran |
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| Abstract: | One-pot, three-component coupling reactions of indole, aromatic aldehydes, and heteroaryl amines under solvent-free conditions lead to the formation of the corresponding novel 3-(N-heteroaryl)(aryl)methyl]indoles in moderate to high yields. The key features of this multi-component reaction are the simple reaction procedure, no organic solvent or acid catalyst, and easy product separation without further purification. |
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